susceptibility of rheumatoid arthritis synovial fibroblasts to fasl- and trail-induced apoptosis is cell cycle-dependent易感性的类风湿性关节炎滑膜成纤维细胞faslu2014u2014trail-induced细胞凋亡是细胞随周期变动.pdf

Available online /content/11/1/R16 Vol 11 No 1 Open Access Research article Susceptibility of rheumatoid arthritis synovial fibroblasts to FasL- and TRAIL-induced apoptosis is cell cycle-dependent 1 1 1 1 2 Noreen Pundt , Marvin A Peters , Christina Wunrau , Simon Strietholt , Carsten Fehrmann , 1 3 1 1 1,4 Katja Neugebauer , Christine Seyfert , Frans van Valen , Thomas Pap and Ingmar Meinecke 1Institute of Experimental Musculoskeletal Medicine, University Hospital Muenster, Domagkstr. 3, Muenster, 48149, Germany 2Institute of Medical Microbiology, University Hospital Muenster, Domagkstr. 10, Muenster, 48149, Germany 3Department of Orthopaedic Surgery, Zeisigwaldkliniken Bethanien Chemnitz, Zeisigwaldstr. 101, Chemnitz, 09130, Germany 4Department of Orthopaedic Surgery, Park-Krankenhaus Leipzig-Suedost GmBH, Struempellstr. 41, Leipzig, 04289, Germany Corresponding author: Thomas Pap, thomas.pap@uni-muenster.de Received: 13 May 2008 Revisions requested: 25 Jun 2008 Revisions received: 24 Nov 2008 Accepted: 5 Feb 2009 Published: 5 Feb 2009 Arthritis Research Therapy 2009, 11:R16 (doi:10.1186/ar2607) This article is online at: /content/11/1/R16 © 2009 Pundt et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Introd