冠心病合并慢性肾病3期患者冠状动脉病变的的特点的探讨.doc

冠心病合并慢性肾病3期患者冠状动脉病变的的特点的探讨 　　【摘要】 目的：探讨冠心病合并慢性肾病3期患者冠状动脉病变的特点。方法：选取汕头大学医学院附属第二医院2012年1月1日-2013年4月18日行冠脉造影术确诊冠心病的119例患者，按照慢性肾病（CKD）分期标准，合并CKD 3期的40例患者为观察A组，未合并CKD 3期的79例患者?槎哉?A组。根据造影结果了解两组冠状动脉病变支数情况，对比两组冠脉病变总体狭窄程度。选取2012年1月1日-2013年1月31日的140例行冠状动脉CTA患者，其中CKD3期患者40例为观察B组，CKD1～2期患者100例为对照B组。根据CTA分析各组冠状动脉斑块钙化积分、发现斑块和严重斑块率、斑块类型的特点。结果：冠脉造影结果，观察A组与对照A组比较，三支冠脉病变例数多、总狭窄积分高，差异均有统计学意义（P0.05）。冠脉CTA结果，观察B组与对照B组比较，冠状动脉钙化积分高，冠脉斑块发现率高，严重斑块发现率高，钙化斑块比例高，差异均有统计学意义（P0.05）。结论：冠心病合并CKD 3期者与肾功能正常者比较：在冠状动脉造影结果中，冠脉病变支数多，复杂病变多，冠脉狭窄程度重；在冠状动脉CTA结果中，冠脉钙化积分高，发现斑块率及钙化的斑块所占比例高，但两组间混合斑块及非钙化斑块比较无差异。 　　【关键词】 冠状动脉粥样硬化心脏病； 慢性肾脏病3期； 冠状动脉造影； 冠状动脉CTA 　　Disscusion of Coronary Artery Lesions Features of Coronary Atherosclerosis Heart Disease Patients Combined with Chronic Kidney Disease 3 Stage/WU Wei-ming，CHEN Yong-xuan.//Medical Innovation of China，2017，14（16）：013-016 　　【Abstract】 Objective：To discussion the coronary artery features of coronary atherosclerosis heart disease patients combiened with chronic kiney disease（CKD） stage 3.Method：From January 2012 to April 2013，119 cases of patients were chosen in the second affiliated hospital，Shantou university medical college，whom had underwent coronarography 119 patients were divided into two groups：79 cases with normal renal function were control A group，whose eGFR≥60 mL/（min?1.73 m2）， combined CKD 3 stage of 40 cases were observation A group，whose eGFR was 30-59 mL/（min?1.73 m2）.From January 2012 to January 2013，140 patients who underwent coronary CT angiography were selected，40 patients of CKD stage 3 were observation B group，100 patients of CKD stage 1-2 were control B group.The coronary calcification score，coronary plaques quantity，coronary plaques severity，coronary plaques characteristics of all groups according the CTA imaging were analysed.Result：The results of coronary angiography，compared with control A group，in observation A group the cases of three coronary stenosis was more，the total coronary artery stenosis score was higher，the differences w