biocompatibility of resin-based dental materials树脂牙科材料的生物相容性.pdf

Materials 2009, 2, 514-548; doi:10.3390/ma2020514 OPEN ACCESS materials ISSN 1996-1944 /journal/materials Review Biocompatibility of Resin-based Dental Materials Keyvan Moharamzadeh *, Ian M. Brook and Richard Van Noort School of Clinical Dentistry, University of Sheffield, Claremont Crescent, Sheffield S10 2TA, United Kingdom; E-Mails: i.brook@Sheffield.ac.uk (I.B.); r.vannoort@Sheffield.ac.uk (R.N.) * Author to whom correspondence should be addressed; k.moharamzadeh@Sheffield.ac.uk; Tel. +44 114 2717931; Fax: +44 114 2265484 Received: 24 February 2009; in revised form: 24 April 2009 / Accepted: 27 April 2009 / Published: 28 April 2009 Abstract: Oral and mucosal adverse reactions to resin-based dental materials have been reported. Numerous studies have examined the biocompatibility of restorative dental materials and their components, and a wide range of test systems for the evaluation of the biological effects of these materials have been developed. This article reviews the biological aspects of resin-based dental materials and discusses the conventional as well as the new techniques used for biocompatibility assessment of dental materials. Keywords: Biocompatibility; dental materials; composite resin. 1. Introduction Biocompatibility is defined as “the ability of a material to function in a specific application in the presence of an appropriate host response” [1]. This definition implies an interaction among a host, a material, and an expected function of the material. All three fa