association between walking speed and age in healthy, free-living individuals using mobile accelerometry—a cross-sectional study步行速度和年龄之间的联系在健康、独立生存的个体使用移动accelerometry-a横断面研究.pdf

Association between Walking Speed and Age in Healthy, Free-Living Individuals Using Mobile Accelerometry—A Cross-Sectional Study 1,2 3 1 1 4 Michaela Schimpl , Carmel Moore , Christian Lederer , Anneke Neuhaus , Jennifer Sambrook , John 3 4 1,2 Danesh , Willem Ouwehand , Martin Daumer * 1 Sylvia Lawry Centre for Multiple Sclerosis Research e.V. – The Human Motion Institute, Munich, Germany, 2 Trium Analysis Online GmbH, Munich, Germany, 3 Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom, 4 Department of Haematology, University of Cambridge and NHS Blood and Transplant, Cambridge, United Kingdom Abstract Context: Walking speed is a fundamental parameter of human motion and is increasingly considered as an important indicator of individuals’ health status. Objective: To evaluate the relationship of gait parameters, and demographic and physical characteristics in healthy men and women. Design, Setting, and Participants: Recruitment of a subsample (n = 358) of male and female blood donors taking part in the Cambridge CardioResource study. Collection of demographic data, measurement of physical characteristics (height, weight and blood pressure) and assessment of 7-day, free-living activity parameters using accelerometry and a novel algorithm to measure walking speed. Participants were a median (interquartile range[IQR]) age of 49 (16) years; 45% women; and had a median (IQR) BMI of 26 (5.4). Main Outcome Measure: Walking speed. Results: In this study, the hypothesis that walking speed declines with age was generated using an initial