underlying factors associated with anemia in amazonian children a population-based, cross-sectional study潜在因素与贫血有关亚马逊的孩子以人群为基础的横断面研究.pdf

Underlying Factors Associated with Anemia in Amazonian Children: A Population-Based, Cross- Sectional Study 1 ´ 2 3 4 5 Marly A. Cardoso *, Kezia K.G. Scopel , Pascoal T. Muniz , Eduardo Villamor , Marcelo U. Ferreira ˜ ˜ 1 Department of Nutrition, School of Public Health, University of Sao Paulo, Sao Paulo, Brazil, 2 Department of Parasitology, Immunology and Microbiology, Federal University of Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil, 3 Department of Health Sciences, Federal University of Acre, Rio Branco, Acre, Brazil, 4 Departments of Environmental Health Sciences and Epidemiology, University of Michigan School of Public Health, Ann Arbor, Michigan, United States of America, 5 Department of ˜ ˜ Parasitology, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, Brazil Abstract Background: Although iron deficiency is considered to be the main cause of anemia in children worldwide, other contributors to childhood anemia remain little studied in developing countries. We estimated the relative contributions of different factors to anemia in a population-based, cross-sectional survey. Methodology: We obtained venous blood samples from 1111 children aged 6 months to 10 years living in the frontier town ˆ of Acrelandia, northwest Brazil, to estimate the prevalence of anemia and iron deficiency by measuring hemoglobin, erythrocyte indices, ferritin, soluble transferrin receptor, and C-reactive protein concentrations.