association between cardiac autonomic function, oxidative stress and inflammatory response in impaired fasting glucose subjects cross-sectional study关联心脏自主神经功能、氧化应激和炎症反应在横断面研究对象的空腹血糖受损.pdf

Association between Cardiac Autonomic Function, Oxidative Stress and Inflammatory Response in Impaired Fasting Glucose Subjects: Cross-Sectional Study 1 1 1 1,4 Ramkumar Thiyagarajan *, Senthil Kumar Subramanian , Nishanth Sampath , Madanmohan Trakroo , 1 2 2 3 Pravati Pal , Zachariah Bobby , Sankar Paneerselvam , Ashok Kumar Das 1 Department of Physiology, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India, 2 Department of Biochemistry, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India, 3 Department of Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India, 4 Advanced Center for Yoga Therapy, Education and Research, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India Abstract Background: The worldwide burden of diabetes in 2030 is projected around 552 million. Diabetes leads to higher risk for cardiovascular diseases (CVD). Altered cardiac autonomic function (CAF) measured by heart rate variability (HRV) is observed in early stages of diabetes but the relationship between impaired fasting glucose (IFG) and HRV is still debatable. The aim of the study was to evaluate the association between CAF, oxidative stress, insulin resistance (IR), and inflammatory response in IFG subjects. Subjects and Methods: Cross-sectional blinded study. Volunteers recruited from health awareness camps underwent CAF and biochemical tests. Based on fasting plasma glucose (FPG) participants (n = 123) were divided into two groups, normal fasting