stem cell banking between traceability and identifiability干细胞银行之间的可跟踪性和可识别性.pdf

Knoppers and Isasi Genome Medicine 2010, 2:73 /content/2/10/73 RE VIE W Stem cell banking: between traceability and identiability Bartha M Knoppers* and Rosario Isasi successful model system for drug discovery, including the Abstract development of new testing methods for drug efficacy, Stem cell banks are increasingly seen as an essential toxicity and safety, and provide a deeper understanding resource of biological materials for both basic and of the processes of human cell differentiation and develop- translational research. Stem cell banks support ment for the treatment of diseases such as cancer [1]. transnational access to quality-controlled and ethically Given the scientific potential of the field, stem cell sourced stem cell lines from dierent origins and of banks are increasingly seen as an essential resource of varying grades. According to the Organisation for biological materials for both basic and translational Economic Co-operation and Development, advances in research. Stem cell banks and registries support trans- regenerative medicine are leading to the development national access to quality-controlled and ethically sourced of a bioeconomy, ‘a world where biotechnology stem cell lines from different origins and of varying contributes to a signicant share of economic grades - for example, research versus clinical. ey are also output’. Consequently, stem cell banks are destined the ‘de facto’ deposito