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无创呼吸机通气对慢性阻塞性肺疾病所致呼吸衰竭疗效观察.doc

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无创呼吸机通气对慢性阻塞性肺疾病所致呼吸衰竭疗效观察   【摘要】 目的:观察无创呼吸机通气治疗慢性阻塞性肺疾病急性期所致呼吸衰竭的效果。方法:根据呼吸衰竭的严重程度和血气分析结果,将患者分成轻、重组两组。除常规治疗方法外,还应用无创面罩固定正压通气。于治疗前,治疗0.5、1、24 h检查动脉血气分析。计算氧合指数。结果:轻组中心率、呼吸频率、pH值治疗前与治疗0.5、1、24 h比较差异有统计学意义(P0.05);PaO2、PaCO2、氧合指数治疗前与治疗0.5、1、24 h比较差异有统计学意义(P0.05)。结论:对于慢性阻塞性肺疾病急性期合并轻度呼吸衰竭患者,除常规治疗外,应采用无创呼吸机通气治疗,可明显提高疗效。   【关键词】 无创通气; 慢性阻塞性肺疾病; 呼吸衰竭   The Effect of Noninvasive Ventilation in Patients with Acute Respiratory Failure of Chronic Obstructive Pulmonary Disease/HUANG Ji-li,LU Ning,LIU Tao,et al.//Medical Innovation of China,2015,12(08):042-044   【Abstract】 Objective:To investigate the effect of noninvasive ventilation in pations with acute respiratory failure of acute exacerbation of chronic obstructive pulmonary disease.Method:The patients were divided into two groups:mild and restructuring,according to the severity of respiratory failure and results of blood gas analysis.The treatments were the application of noninvasive positive pressure ventilation mask fixation and conventional treatment.Blood gas analysis of the arterial were checked in 0,0.5,1,24 hour in time of treatment.Result:In mild group:it had significant difference between 0 hour and 0.5,1,24 hour in time of treatment in the heart rate,respiratory frequency,pH value(P0.05);and significant difference in PaO2,PaCO2,oxygenation index(P0.01).Conclusion:Noninvasive ventilation can effective treat mild respiratory failure of acute exacerbation of chronic obstructive pulmonary disease in addition to the routine treatment.   【Key words】 Noninvasive ventilation; Chronic obstructive pulmonary disease; Respiratory failure   First-author’s address:Guangming New District Central Hospital,Shenzhen 518107,China   doi:10.3969/j.issn.1674-4985.2015.08.015   慢性阻塞性肺疾病(COPD)是一种常见病、多发病,病死率高[1]。它所致的严重并发症:呼吸衰竭、组织缺氧和二氧化碳潴留,危及患者的生命,若不及时治疗和抢救,就会出现不可逆的损害,甚至突然心跳骤停。那么及时地纠正缺氧是COPD合并呼吸衰竭首要治疗措施。临床上常用药物有一定的局限性,而有创呼吸机通气治疗副作用、并发症多。而无创呼吸机通气(NIPPV)改善组织缺氧已被临床所证明有效,但应用较少,究其原因多样:不但与呼吸机的性能和舒适性有关,而且与临床的经验有关[2]。本研究致力于NIPPV治疗COPD所致的呼吸
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