无创呼吸机治疗慢性阻塞性肺疾病急性加重期合并呼吸衰竭临床研究.doc

无创呼吸机治疗慢性阻塞性肺疾病急性加重期合并呼吸衰竭临床研究 　　[摘要] 目的 慢性阻塞性肺疾病（COPD）急性加重期合并呼吸衰竭患者采用无创呼吸机治疗后的疗效分析。 方法 选取2012年1月～2014年2月来我院内科接受治疗的慢性阻塞性肺疾病急性加重期伴有呼吸衰竭患者，按照不同治疗方法分为实验组43例和对照组47例，对照组采用常规治疗方法，实验组在对照组治疗的基础上采用无创呼吸机进行治疗，观察两组疗效。 结果 实验组治疗后24 h各项指标优于对照组（P0.05），两组总有效率分别为95.3%、80.9%，差异有统计学意义（P0.05）。 结论 无创呼吸机用于治疗慢阻肺伴呼吸衰竭，降低死亡率。 　　[关键词] 呼吸衰竭；无创呼吸机；慢性阻塞性肺疾病 　　[中图分类号] R563.9 [文献标识码] B [文章编号] 1673-9701（2014）36-0124-03 　　Clinical study of non-invasive ventilation in the treatment of patients with chronic obstructive pulmonary disease （COPD） in acute exacerbation combined with respiratory failure 　　DING Hong 　　Department of Internal Medicine， Jiangsu Province Suzhou Industrial Park Loufeng Hospital， Suzhou 215125， China 　　[Abstract] Objective To study the curative effect of non-invasive ventilation in the treatment of patients with Chronic obstructive pulmonary disease （COPD） in acute exacerbation combined with respiratory failure. Methods Patients from 2012 January to 2014 February in our hospital for treatment of chronic obstructive pulmonary disease were divided into experimental group with 43 cases and control group with 47 cases according to the methods of treatment.The conventional treatment method was applied in the control group， and the experimental group were treated with noninvasive ventilator based on the treatment of control group. The curative effect was compared between two groups. Results After the treatment， the indexes of 24 h in experimental group were better than that in control group. The total efficiency of two groups were 95.3% and 80.9% with statistical significance （P0.05）. Conclusion Noninvasive ventilator could reduce the mortality rate in treatment of COPD with respiratory failure. 　　[Key words] Respiratory failure； Noninvasive ventilation； Chronic obstructive pulmonary disease 　　慢性阻塞性肺疾病（COPD），主要是指肺气肿和慢性支气管炎不可逆性的气道阻塞[1]，其病死率、发病率较高。早期患者的气短或呼吸困难症状常在活动时出现，后期严重时在休息时也会出现这种症状。在COPD晚期可并发呼吸系统衰竭，若患者得不到及时治疗，可能会丧失生命，因此，有效的治疗对COPD伴有呼吸衰竭患者是很有必要的。以往临床上采取人工气道机械通气对COPD伴呼吸衰竭患者进