comparative and joint analysis of two metagenomic datasets from a biogas fermenter obtained by 454-pyrosequencing比较和联合分析的两个宏基因组数据集从454 -焦磷酸测序获得的沼气发酵罐.pdf

Comparative and Joint Analysis of Two Metagenomic Datasets from a Biogas Fermenter Obtained by 454- Pyrosequencing 1 1 1 1 ¨ 2 Sebastian Jaenicke , Christina Ander , Thomas Bekel , Regina Bisdorf , Marcus Droge , Karl-Heinz 3 ¨ 1,4 2 5 1 1 Gartemann , Sebastian Junemann , Olaf Kaiser , Lutz Krause , Felix Tille , Martha Zakrzewski , Alfred ¨ 6 ¨ 6. 1 . Puhler , Andreas Schluter , Alexander Goesmann * 1 Computational Genomics, Center for Biotechnology (CeBiTec), Bielefeld University, Bielefeld, Germany, 2 Roche Diagnostics GmbH, Penzberg, Germany, 3 Department of ¨ ¨ Genetechnology/Microbiology, Bielefeld University, Bielefeld, Germany, 4 Department of Periodontology, University Hospital Munster, Munster, Germany, 5 Division of Genetics and Population Health, Queensland Institute of Medical Research, Herston, Australia, 6 Institute for Genome Research and Systems Biology, Center for Biotechnology (CeBiTec), Bielefeld University, Bielefeld, Germany Abstract Biogas production from renewable resources is attracting increased attention as an alternative energy source due to the limited availability of traditional fossil fuels. Many countries are promoting the use of alternative energy sources for sustainable energy production. In this study, a metagenome from a production-scale biogas fermenter was analysed employing Roche’s GS FLX Titanium