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Open access, freely available online Synopses of Research Articles Charting the Interplay between Structure and Dynamics in Complex Networks DOI: 10.1371/journal.pbio.0030369 While intelligent-design proponents an “excellent correlation” between enjoy their 15 minutes of fame denying stability and motif abundance. Higher the role of evolutionary forces in stability motifs were more abundant in generating complex networks in nature, the real networks, while low-stability scientists are probing the organizing motifs were absent, suggesting that principles that govern these networks. the nonrandom character of network Traditional models of complex networks organization is driven by the structural assumed that connections between stability of network motifs. To see how units—such as genes, proteins, these motifs might operate as functional neurons, or species—occur randomly. units, the authors used microarray data These notions changed as studies of from yeast subjected to fi ve different protein interaction networks and other