associations among raceethnicity, apoc-iii genotypes, and lipids in hiv-1-infected individuals on antiretroviral therapy协会在raceethnicity、apoc-iii基因型和脂质在hiv-1-infected个人抗逆转录病毒治疗.pdf

PLoS MEDICINE Associations among Race/Ethnicity, ApoC-III Genotypes, and Lipids in HIV-1-Infected Individuals on Antiretroviral Therapy 1* 2 3 1 3 3 4 Andrea S. Foulkes , David A. Wohl , Ian Frank , Elaine Puleo , Stephanie Restine , Megan L. Wolfe , Michael P. Dube , 3 3 Pablo Tebas , Muredach P. Reilly 1 School of Public Health and Health Sciences, University of Massachusetts, Amherst, Massachusetts, United States of America, 2 University of North Carolina, Chapel Hill, North Carolina, United States of America, 3 School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America, 4 Indiana University, Indianapolis, Indiana, United States of America Competing Interests: The authors A B S T R A C T have declared that no competing interests exist. Background Author Contributions: ASF, DAW, IF, MPD, PT, and MPR designed the Protease inhibitors (PIs) are associated with hypertriglyceridemia and atherogenic study. ASF and EP performed dyslipidemia. Identifying HIV-1-infected individuals who are at increased risk of PI-related statistical analysis of the data. MPD dyslipidemia will facilitate therapeutic choices that maintain viral suppression while reducing enrolled patients. ASF, DAW, IF, MPD, PT, and MPR contributed to risk of atherosclerotic diseases. Apolipoprotein C-III (apoC-III) gene variants, which vary by race/ writing the paper. ASF, IF and MPR ethnicity