decidual macrophages are significantly increased in spontaneous miscarriages and over-express fasl a potential role for macrophages in trophoblast apoptosis蜕膜巨噬细胞显著增加在自发流产和过表达fasl巨噬细胞在滋养层细胞凋亡的潜在作用.pdf

Int. J. Mol. Sci. 2012, 13, 9069-9080; doi:10.3390/ijm OPEN ACCESS International Journal of Molecular Sciences ISSN 1422-0067 /journal/ijms Article Decidual Macrophages Are Significantly Increased in Spontaneous Miscarriages and Over-Express FasL: A Potential Role for Macrophages in Trophoblast Apoptosis Sabine Guenther 1,†, Thomas Vrekoussis 1,†, Sabine Heublein 1, Birgit Bayer 2, David Anz 3, Julia Knabl 1, Iordanis Navrozoglou 4, Darius Dian 1, Klaus Friese 1,5, Antonis Makrigiannakis 6 and Udo Jeschke 1,* 1 Department of Obstetrics and Gynecology, Innenstadt Campus, Ludwig-Maximilians University of Munich, Munich D-80377, Germany; E-Mails: honeybine@gmx.de (S.G.); thomas_vrekoussis@yahoo.gr (T.V.); sabine.heublein@med.uni-muenchen.de (S.H.); julia.knabl@med.uni-muenchen.de (J.K.); darius.dian@med.uni-muenchen.de (D.D.); klaus.friese@med.uni-muenchen.de (K.F.) 2 Department of Legal Medicine, Ludwig-Maximilians University of Munich, Munich D-80377, Germany; E-Mail: birgit.bayer@med.uni-muenchen.de 3 Department of Internal Medicine, Pharmacological ward, Ludwig-Maximilians University of Munich, Munich D-80377, Germany; E-Mail: david.anz@med.uni-muenchen.de 4 Department of Obstetrics and Gynecology, Medical School, University of Ioannina, Ioannina 45110, Greece; E-Mail: inavro@yahoo.gr 5 Department of Obstetrics and Gynecology, Grosshadern Campus, Ludwig-Maximilians University of Munich, Munich D-80377, Germany 6 Department of Obstetrics and Gynecology, Medical School, Univers