复旦奥医欣丽康：大豆异黄酮的药理学研究进展.pdf

维普资讯 承 德 医 学 院 学 Vo1．21No．12004 JOURNAL0FCHENGDEMEDICALCOLLEGE 溶酶原活化剂 (TPA)的信号序列。这些融合基因体内应用后， 408． 都检测到显著的抗体应答，增强了核酸疫苗的保护作用。 [9] ChaplinPJ，De RoseR，BoyleJS，eta1．Targetingimproves 【参考文献】 the efficacy ofa DNA vaccine againstCorynebaeterium [1] ChowYH，ChiangBL，LeeYL，eta1．DevelopmentofThl pseudotubereulosisinsheep[J]．InfectImmun，1999，67 and Th2populationsandthenatureofimmuneresponses (12)：6434． tohepatitisB virusDNA vaccinescan bemodulated by [1O] YouZ，HuangX，HesterJ，eta1．Targetingdendriticcells codeliveryofvariouseytokinegenes[J]．JImmunol，1998， toenhanceDNAvaccinepotency[J]．CancerRes，2001，61 160(3)：1320． (9)：3704． [2] XinKQ，LuY，HamajimaK，eta1．Immunizationof [11] HungCF，HsuKF，ChengwF，eta1．Enhancementof RANTES expression plasmid with a DNA vaccine ca— DNA vaccinepotencyby linkageofantigengenetoagene hancesHIV一1一specificimmunityEJ]．ClinImmunol，1999， encod ingtheextracellulardomain ofFms——liketyrosineki—— 92(1)：90． nase3-ligand[J]．CancerRes，2001，61(3)：1080． [33 KimJJ，YangJS，DentchevT，eta1．Chemokinegeneadju— [12] MwangiW ，BrownWC，LewinHA，eta1．DNA—encoded vants can modulateimmune responsesinduced by DNA fetal liver tyrosine kinase 3 ligand and granulocyte vaccines[J]．JInterferonCytokineRes，2000，20(5)：487． macrophage——colony——stimulating factor increase dendritic [43 BiragynA，BelyakovIM，ChowYH，eta1．DNAvaccines eellrecruitmentto theinoculation siteandenhance