早期诊断和干预脓毒症治疗临床研究.doc
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早期诊断和干预脓毒症治疗临床研究
DOI:10.16662/j.cnki.1674-0742.2017.11.106
[摘要] 目的 探?并总结早期诊断和干预措施对于脓毒症治疗的临床效果。方法 方便选取2015年10月―2016年11月期间在该院ICU接受诊断和治疗的脓毒症患者90例,按病情严重程度分为脓毒症组(48例)和严重脓毒症组(42例)。观察所有患者c-反应蛋白(CRP)、白细胞计数(WBC)、内毒素水平、血清降钙素原水平(PCT)以及中性粒细胞比例等相关炎症指标的检验结果,并对两组检验结果进行比较。对脓毒症组患者采取早期干预措施配合临床治疗方案,严重脓毒症组患者仅采取常规治疗方案,观察比较两组患者临床治疗效果。结果 脓毒症组患者PCT值为(0.21±0.17)μg/L,CRP为(28.1±22.4)mg/L,WBC为(7.93±5.62)×109/L,中性粒细胞数为(0.73±0.21),对比以上数据发现脓毒症组患者水平均低于严重脓毒症组患者(P0.05);治疗后脓毒症组患者PT下降至(13.4±0.6)s,明显低于严重脓毒症组患者水平(P0.05),且治疗后脓毒症组PLT上升至(118.3±12.3)×109/L,明显高于严重脓毒症组患者(P0.05);脓毒症组患者入住ICU时间为(4.12±1.03)d,明显短于严重脓毒症组患者,机械通气时间为(78.53±18.62)h,明显早于严重脓毒症组患者(P0.05)。结论 观察血清炎症因子对于早期诊断脓毒症有重要临床意义,早期干预对于脓毒症的临床治疗有明显效果,能够减少患者住院时间,提高治疗有效率。
[关键词] 临床诊断;炎症指标;早期干预;脓毒症
[中图分类号] R631 [文献标识码] A [文章编号] 1674-0742(2017)04(b)-0106-03
Clinical Research on Early Diagnosis and Intervention of Sepsis Treatment
SHEN Qiang
ICU, Guanxian Central Hospital, Guanxian, Shandong Province, 252500 China
[Abstract] Objective To discuss and summarize the clinical effect of early diagnosis and intervention of sepsis treatment. Methods Convenient selection 90 cases of patients with sepsis treated in the ICU in our hospital from October 2015 to November 2016 were selected and divided the sepsis group with 48 cases and severe sepsis group with 42 cases, and the CRP, WBC, endotoxin level, PCT and percentage of neutrophils and other related inflammatory indexes of all patients were observed, and the test Results were compared, and the sepsis group adopted the early intervention measures and clinical treatment plan, while the severe sepsis group only adopted the routine treatment plan, and the clinical treatment effect was compared. Results The PCT, CRP, WBC and neutrophil count in the sepsis group were lower than those in patients with severe sepsis, which were respectively (0.21±0.17)μg/L, (28.1±22.4)mg/L and (7.93±5.62)×109/L and(0.73±0.21)(P [Key words] Clinical diagnosis; Inflammatory factor; Early intervention; Sepsis
脓毒症
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