study of oh● radicals in human serum blood of healthy individuals and those with pathological schizophrenia哦●自由基的研究在人类血清血液健康的个人和那些病态的精神分裂症.pdf

Int. J. Mol. Sci. 2011, 12, 401-409; doi:10.3390/ijm OPEN ACCESS International Journal of Molecular Sciences ISSN 1422-0067 /journal/ijms Article ● Study of OH Radicals in Human Serum Blood of Healthy Individuals and Those with Pathological Schizophrenia Elena I. Korotkova 1,*, Bashkim Misini 2, Elena V. Dorozhko 1, Mariya V. Bukkel 1, 1 2 Evgeniy V. Plotnikov and Wolfgang Linert 1 Tomsk Polytechnic University, Lenin av., 30, 634050, Tomsk, Russia 2 Institute of Applied Synthetic Chemistry, Vienna University of Technology, Getreidemarkt 9/163AC A–1060 Vienna, Austria; E-Mail: wlinert@mail.zserv.tuwien.ac.at (W.L.) * Author to whom correspondence should be addressed; E-Mail: eikor@mail.ru; Tel.: +7-382-2-563-832; Fax: +7-382-2-563-435. Received: 19 November 2010; in revised form: 29 December 2010 / Accepted: 4 January 2011 / Published: 14 January 2011 Abstract: The human body is constantly under attack from free radicals that occur as part of normal cell metabolism, and by exposure to environmental factors such as UV light, cigarette smoke, environmental pollutants and gamma radiation. The resulting “Reactive Oxygen Species” (ROS) circulate freely in the body with access to all organs and tissues, which can have serious repercussions throughout the body. The body possesses a number of mechanisms both to co