变应性鼻炎患者血清白细胞介素含量检测及临床价值_阙镇如冉骞林丹琪张智斌蔡继一许玉.pdf
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DOI :10.13210/ki.jhmu082 网络出版时间:2014-01-24 22:04
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变应性鼻炎患者血清白细胞介素含量检测及临床价值
阙镇如 冉骞 林丹琪 张智斌 蔡继一 许玉 黄钦辉
解放军第180 医院耳鼻咽喉科 福建 泉州 362008
摘要:目的:研究变应性鼻炎患者血清白细胞介素含量及临床价值。方法:将2011 年
1 月-2013 年5 月在我院就诊的变应性鼻炎患者纳入研究的观察组,同期在我院接受体检的
健康者纳入研究的对照组,检测血清白细胞介素IL-4 、IL-5、IL- 17、IL-33 含量以及气道功
能指标,并进行临床症状评分。结果:(1)观察组患者的IL-4 、IL-5、IL- 17、IL-33 水平高
于对照组健康者;(2 )观察组患者的PEF 、FEV1/FVC 均低于对照组健康者,喷嚏、流涕、
鼻塞、鼻痒评分均高于对照组健康者;(3 )血清IL-4 、IL-5、IL- 17、IL-33 水平与PEF 、FEV1/FVC
呈负相关,与喷嚏、流涕、鼻塞、鼻痒评分呈正相关。结论:血清白细胞介素含量且具有检
测方便、客观性强的优势,能够便捷、准确、客观的反应变应性鼻炎患者的整体病情,临床
应用价值明确。
关键词:变应性鼻炎;白细胞介素;气道功能;
The detection of serum interleukin levels in allergic rhinitis patients and its clinical
value
QUE Zhen-ru, RAN Qian, LIN Dan-qi, et al
Department of Otorhinolaryngology,Quanzhou 180 Hospital of PLA,Quanzhou
362008,China
Abstract: Objective: To study the serum interleukin levels of allergic rhinitis patients and its
clinical value. Methods: allergic rhinitis patients in our hospital from 2011 January-2013 May
were enrolled in the observation group and healthy people underwent physical examination were
enrolled in the control group. Then serum IL-4,IL-5, IL- 17, IL-33 content and airway function
were detected, clinical symptom score were evaluated. Results:(1) IL-4,IL-5, IL- 17, IL-33
contents of observation group were higher than those of control group; (2) PEF, FEV1/FVC of
observation group
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