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biomarkers of oxidative stress and heavy metal levels as indicators of environmental pollution in african cat fish (clarias gariepinus) from nigeria ogun river生物标记物的氧化应激和重金属水平作为环境污染的指标在非洲猫鱼(高清晰gariepinus)从尼日利亚ogun河.pdf

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Int. J. Environ. Res. Public Health 2007, 4(2), 158-165 International Journal of Environmental Research and Public Health ISSN 1661-7827 © 2007 by MDPI Biomarkers of Oxidative Stress and Heavy Metal Levels as Indicators of Environmental Pollution in African Cat Fish (Clarias gariepinus) from Nigeria Ogun River E. O. Farombi*, O. A. Adelowo, and Y. R. Ajimoko Drug Metabolism and Toxicology Research Laboratories, Department of Biochemistry, College of Medicine, University of Ibadan, Nigeria *Correspondence to Dr. E. Olatunde Farombi; Email: olatunde_farombi@ Received: 10 January 2007 / Accepted: 15 June 2007 / Published: 30 June 2007 Abstract: Levels of Zn, Cu, Cd, As, and Pb in the kidney, Liver, Gills and Heart of African cat fish (Clarias gariepinus) from the Ogun River in Ogun State located close to six major industries in the South Western part of Nigeria, were determined using Bulk Scientific Atomic Absorption Spectrophotometer. Fishes were also collected from Government owned fish farm in Agodi, Ibadan which was considered a reference site. The activities of superoxide dismutase (SOD), catalase (CAT), glutathione S-transferase (GST), glutathione (GSH) concentration and malondialdehyde
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