糖尿病患者监测糖化血红蛋白的临床意义探究.doc

精品论文 参考文献 糖尿病患者监测糖化血红蛋白的临床意义探究 崔自明 　　（北京崇文光明医院 北京 100061） 　　【摘要】目的：探究糖尿病患者检测糖化血红蛋白的临床意义。方法：将2012年1月—2014年1月我院收治的120例糖尿病患者作为本次研究的观察组，另选取同期行体检的健康人群120位为对照组，比较两组研究对象糖化血红蛋白监测情况，并分析观察组患者发生糖尿病并发症的情况。结果：观察组患者在血糖测定、总胆固醇测定以及HbA1c测定比较上均显著高于对照组（P＜0.05），而HbA1c＞8%的患者中发生周围神经病变、脑血管病变的患者明显多于HbA1cle;8%的患者（P＜0.05），差异有统计学意义。结论：对糖尿病患者进行糖化血红蛋白监测具有重要的诊断意义，同时还能有效监测患者的合并症以及并发症发生情况，具有重要的临床推广价值。 　　【关键词】糖尿病；糖化血红蛋白；监测；诊断 　　【中图分类号】R446 【文献标识码】A 【文章编号】2095-1752（2015）03-0061-02 　　To explore the clinical significance of the diabetes monitoring glycated hemoglobin Cui Ziming. Beijing Chongwen Guangming hospital, Beijing 100061, China 　　【Abstract】Objective To explore the diabetic patients the clinical significance of the detection of glycosylated hemoglobin. Methods Will be in January 2012 - January 2014 cases of diabetic patients of our hospital as the study group, the other selected row over the same physical examination of healthy people 120 as the control group, compared two groups glycosylated hemoglobin monitoring situation, and analyzes the situation of the observation group of patients with diabetes complications. Results Observation group of patients in the determination of blood glucose, total cholesterol and HbA1c measurement comparisons were significantly higher than control group (Plt;0.05), while HbA1c gt; occurring in 8% of patients with peripheral neuropathy, cerebrovascular disease in patients with significantly more than the HbA1c of 8% or less of patients (Plt;0.05), the difference was statistically significant. Conclusions For glycosylated hemoglobin monitoring of patients with diabetes has important diagnostic significance, as well as complications and complications in patients with effective monitoring, has the important clinical value. 　　【Key words】Diabetes; Glycated hemoglobin; Monitoring; The diagnosis 　　糖尿病（DM）是一种以血糖持续升高为特征的慢性代谢性疾病，是机体胰岛素分泌相对或绝对不足造成的一系列以糖代谢、脂肪代谢、蛋白质代谢出现紊乱的综合性疾病。现阶段对于糖尿病的诊断主要依靠糖化血红蛋白（HbA1c），临床上将HbA1cge;6.5%作为糖尿病的主要诊断切点，但对于HbA1c＜