人感染猪流感诊疗方案(2009版)(Diagnosis and treatment of human swine influenza (2009 edition)).doc
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人感染猪流感诊疗方案(2009版)(Diagnosis and treatment of human swine influenza (2009 edition))
Diagnosis and treatment of human swine influenza (2009 edition)
Swine influenza is an acute, zoonotic respiratory tract infection caused by influenza a (type a) influenza virus. This disease occurs frequently in pigs and rarely causes pigs to die (the fatality rate of pigs is 1 ~ 4%). Humans are rarely infected with the swine flu virus, but they have also found some cases of human swine flu, mostly people with direct contact with sick pigs. In March 2009, Mexico and the United States there are people with swine flu virus, such as for type a influenza virus, subtype h1n1 swine flu strain, the strain contain swine flu, avian and human influenza three influenza virus gene fragments, is a kind of new swine flu virus, can infect people. The clinical early symptoms of swine flu are similar to those of influenza, with fever, cough, fatigue, loss of appetite and other symptoms such as diarrhea or vomiting. The disease can progress rapidly, sudden high fever, pneumonia, can appear respiratory failure, multiple organ damage, leading to death.
I. etiology
The swine flu virus is a virus called influenza virus a. The typical virus particles are spherical, with a diameter of 80nm ~ 120nm, with a capsule. There are a number of radiated glycoproteins in the capsule, the hemagglutinin ha, the neuraminidase na and the m2 protein. The nucleic capsid is the nucleic capsid of the virus particle, with a spiral symmetry and a diameter of 10 nm. The swine influenza virus is a single negative stranded RNA virus, with a genome of about 13.6 KB, consisting of eight separate fragments of varying sizes. Although different subtypes can form a wide variety of influenza virus serotypes, the serotypes that can cause human infection with swine influenza viruses mainly include h1n1, h1n2 and h3n2.
The swine flu virus as a virus capsule membrane, in this paper, diethyl ether, chloroform, acetone and other organic solven
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