糖尿病肾病早期诊断与糖化血红蛋白的相关性研究.doc

精品论文 参考文献 糖尿病肾病早期诊断与糖化血红蛋白的相关性研究 桑植县民族中医院 湖南桑植 427100 【摘 要】目的：探究临床上糖尿病肾病早期诊断与糖化血红蛋白的相关性。方法：选择我院2015年1月-2016年1月收治的68例确诊为糖尿病肾病的患者为研究对象，设为观察组；另外选择同期经相同检查，但最终确诊为健康人群的30例为对照组，对比两组U-mAlb以及HbA1c；此外在观察组中，根据HbA1c值将其分为血糖控制良好组（HbA1clt;6.5%）36例、血糖控制一般组（6.5%lt;HbA1clt;8%）18例、血糖控制较差组（HbA1cgt;8%）14例，对比分析这三组的U-mAlb以及HbA1c的关系。结果：观察组所测定的U-mAlb以及HbA1c值均明显高于对照组，差异有统计学意义（Plt;0.05）；在血糖控制情况的分组相比较中，发现HbA1c与U-mAlb呈现明显的正相关关系，且每组间差异有统计学意义（Plt;0.05）。结论：临床上通过测定患者U-mAlb以及HbA1c的变化，可以及时有效的对糖尿病肾病进行检测以及监测，对糖尿病肾病的早期诊断有较高的诊断价值，值得临床应用推广。 【关键词】大剂量速尿；多巴胺；早期肾功能衰竭；临床疗效 [Abstract] objective：to explore clinical diabetic nephropathy early diagnosis and the correlation of glycosylated hemoglobin. Methods：from January 2015 - January 2016 68 cases diagnosed with diabetes nephropathy patients as the research object，set as observation group；During the same period by the same check another option，but eventually diagnosed with 30 cases of healthy people as control group，compared two groups of U - mAlb and HbA1c；In addition in the observation group，according to HbA1c values will be divided into good blood sugar control（HbA1c lt; 6.5%）36 cases，blood sugar control group（6.5% lt; HbA1c lt; 8%），18 cases，poor blood sugar control groups（HbA1c gt; 8%），14 cases，comparative analysis of the three sets of U - mAlb，as well as the relationship between HbA1c. Results：the observation group measured by U - mAlb and HbA1c values were significantly higher than that of control group，the difference was statistically significant（P lt; 0.05）；In blood sugar control，in comparison with the grouping of HbA1c and U - mAlb present obvious positive correlation，and the difference between each group was statistically significant（P lt; 0.05）. Conclusions：U - mAlb and patients with clinically by measuring the change of HbA1c，can be timely and effective testing and monitoring of diabetes，kidney disease，early diagnosis of diabetic nephropathy have high diagnostic value，worthy of clinical promotion. [Key words] high-dose furosemide；Dopamine；The ea