specific ige anti-ascaris in brazilian children and adolescents特定的ige anti-ascaris在巴西儿童和青少年.pdf

REVIEWS Specific IgE Anti-Ascaris in Brazilian Children and Adolescents Emanuel S. Sarinho, MD, PhD, Décio Medeiros, Almerinda Silva, and José Ângelo Rizzo primary immunodeficiency with recurrent infections. Despite Abstract: From an article published by our group by Medeiros et al, that, serum total IgE high levels in patients from poor coun- we discuss and review the literature on the role of serum specific tries frequently indicate chronic parasitic infection, especially anti-ascaris IgE in patients with respiratory allergies living in coun- tries where helminthic infestations are common. Medeiros et al by geohelminths, which stimulate the production of poly- clonal IgE.3,4 conducted a study using 101 patients aged 12 to 21 years with Ascaris lumbricoides tend to cause chronic infections, respiratory allergy. Median IgE level was 660 IU/mL. Serum spe- which can interfere with TH2 response. It is possible that this cific anti-ascaris IgE was positive in 73% (74/101) of the individu- mechanism enables parasite survival and may allow the host als, but parasitological stool examination yielded positive results in to escape from potentially damaging inflammation in the only 33