孟鲁司特纳治疗小儿持续性哮喘疗效评估与研究.doc

孟鲁司特纳治疗小儿持续性哮喘疗效评估与研究 　　[摘要] 目的 评估与研究孟鲁司特钠治疗小儿持续性哮喘的临床治疗效果。方法 方便选择2013年1月―2015年12月该院收治的64例持续性哮喘患儿作为研究对象，根据随机数字法将64例哮喘患儿均分成对照组与观察组，其中对照组仅应用布地奈德治疗，而观察组在对照组用药基础上联合孟鲁司特钠治疗，对比两组哮喘患儿的治疗效果。结果 观察组痊愈25例，有效6例，无效1例，总有效率为96.88%；对照组痊愈18例，有效6例，无效8例，总有效率为75.00%；对比观察组与对照组治疗总有效率，观察组治疗效果更为理想，两组对比差异有统计学意义（P0.05）；治疗后6个月随访，观察组哮喘复发1例，哮喘复发率达3.13%，对照组哮喘复发6例，哮喘复发率达18.75%，对比两组患儿复发率，观察组复发率明显比对照组低，两组对比差异有统计学意义（P0.05）。结论 孟鲁司特钠治疗小儿持续性哮喘疗效理想，能明显提高临床治疗效果，降低哮喘复发率，值得推广应用。 　　[关键词] 孟鲁司特钠；持续性哮喘；治疗效果；复发 　　[中图分类号] R562 [文献标识码] A [文章编号] 1674-0742（2017）01（b）-0022-03 　　[Abstract] Objective To evaluate and research the curative effect of montelukast in treatment of persistent asthma in children. Methods Convenient selection 64 cases of children with persistent asthma admitted and treated in our hospital from January 2013 to December 2015 were selected as the research objects and randomly divided into two groups， the control group only adopted the budesonide， while the observation group adopted the montelukast on the basis of the control group， and the treatment effect of the two groups was compared. Results 25 cases were cured， 6 cases were effective， 1 case was ineffective， and the total effective rate was 96.88% in the observation group， and 18 cases were cured， 6 cases were effective， 8 cases were ineffective， and the total effective rate was 75.00% in the control group， and the treatment effect in the observation group was more ideal than that in the control group， and the difference between the two groups had statistical significance（P0.05）， after 6-month treatment， the follow-up showed that the recurrence of asthma was in 1 case， and the recurrence rate of asthma reached 3.13% in the observation group， and the recurrence of asthma was in 6 cases， and the recurrence rate of asthma reached 18.75%， and the recurrence rate in the observation group was lower than that in the control group， and the difference had statistical significance（P0.05）. Conclusion The curative effect of montelukast in treatment