u-curve association between timing of renal replacement therapy initiation and in-hospital mortality in postoperative acute kidney injuryu曲联系肾脏替代治疗的时机发起并在术后急性肾损伤患者住院死亡率.pdf

U-Curve Association between Timing of Renal Replacement Therapy Initiation and In-Hospital Mortality in Postoperative Acute Kidney Injury 1 2,3 4 5 4 2 Chih-Chung Shiao , Wen-Je Ko , Vin-Cent Wu , Tao-Min Huang , Chun-Fu Lai , Yu-Feng Lin , Chia- 4 4 2 4 3 4 Ter Chao , Tzong-Shinn Chu , Hung-Bin Tsai , Pei-Chen Wu , Guang-Huar Young , Tze-Wah Kao , Jenq- 4 4 4 4 3 4 Wen Huang , Yung-Ming Chen , Shuei-Liong Lin , Ming-Shou Wu , Pi-Ru Tsai , Kwan-Dun Wu , Ming- Jiuh Wang6*, on behalf of the National Taiwan University Hospital Study Group on Acute Renal Failure (NSARF) 1 Division of Nephrology, Department of Internal Medicine, Saint Mary’s Hospital Luodong, and Saint Mary’s Medicine, Nursing and Management College, Yilan, Taiwan, 2 Department of Traumatology, National Taiwan University Hospital, Taipei, Taiwan, 3 Department of Surgery, National Taiwan University Hospital, Taipei, Taiwan, 4 Division of Nephrology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan, 5 Division of Nephrology, Department of Internal Medicine, National Taiwan University Hospital Yun-Lin Branch, Douliu City, Yunlin County, Taiwan, 6 Department of Anesthesiology and Forensic Medicine, National Taiwan University Hospital, Taipei, Taiwan Abstract Background: Postoperative acute kidney injury (AKI) is associated with poor outcomes in surgical patients. This study aims to evaluate whether the timing of renal replacement therapy (RRT) initiation af