systematic review of determinants of mortality in high frequency oscillatory ventilation in acute respiratory distress syndrome系统评价因素的死亡率在急性呼吸窘迫综合征的高频振荡通气.pdf

Available online /content/10/1/R34 Vol 10 No 1 Open Access Research Systematic review of determinants of mortality in high frequency oscillatory ventilation in acute respiratory distress syndrome Casper W Bollen, Cuno SPM Uiterwaal and Adrianus J van Vught University Medical Centre Utrecht, The Netherlands Corresponding author: Casper W Bollen, c.w.bollen@umcutrecht.nl Received: 19 Sep 2005 Revisions requested: 9 Nov 2005 Revisions received: 9 Dec 2005 Accepted: 27 Jan 2006 Published: 20 Feb 2006 Critical Care 2006, 10:R34 (doi:10.1186/cc4824) This article is online at: /content/10/1/R34 © 2006 Lapinsky et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Introduction Mechanical ventilation has been shown to cause observational studies were included. Data from cohorts lung injury and to have a significant impact on mortality in acute comparing survivors with non-survivors showed differences in respiratory distress syndrome. Theoretically, high frequency age (42.3 versus 51.2 years), prior time on conventional oscillatory ventilation seems an ideal lung protective ventilation mechanical ventilation (4.0 versus 6.2 days), APACHE II score mode. This review evaluates determinants of mortality during (22.4 versus 26.1), pH (7.33 versus 7.26) and oxygenation use of high frequency oscillatory ventilation. index (26