damaged intestinal epithelial integrity linked to microbial translocation in pathogenic simian immunodeficiency virus infections受损的肠上皮的完整性与致病性微生物易位猴免疫缺陷病毒感染.pdf

Damaged Intestinal Epithelial Integrity Linked to Microbial Translocation in Pathogenic Simian Immunodeficiency Virus Infections 1 2 2 1 3 4 Jacob D. Estes *, Levelle D. Harris , Nichole R. Klatt , Brian Tabb , Stefania Pittaluga , Mirko Paiardini , 5 6 6 7 2 G. Robin Barclay , Jeremy Smedley , Rhonda Pung , Kenneth M. Oliveira , Vanessa M. Hirsch , Guido 4 8 9 10 1 Silvestri , Daniel C. Douek , Christopher J. Miller , Ashley T. Haase , Jeffrey Lifson , Jason M. Brenchley2* 1 AIDS and Cancer Virus Program, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland, United States of America, 2 Lab of Molecular Microbiology, NIAID, NIH, Bethesda, Maryland, United States of America, 3 Lab of Pathology, NCI, NIH, Bethesda, Maryland, United States of America, 4 Department of Pathology and Laboratory of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America, 5 Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, Scotland, 6 Laboratory Animal Science Program, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland, United States of America, 7 AdvanDX, Inc., Woburn, Massachusetts, United States of America, 8 Human Immunology Section, Vaccine Research Center, NIAID, NIH, Bethesda, Maryland, United States of America, 9 Center for Comparative Medicine, California National Primate Research Center, University of California, Davis, California, United States of America, 10 Department of Microbiology, Medical School, University of Minnesota, Min