steroids in the treatment of iga nephropathy to the improvement of renal survival a systematic review and meta-analysis类固醇治疗iga肾病肾功能的改善生存系统回顾和荟萃分析.pdf

Steroids in the Treatment of IgA Nephropathy to the Improvement of Renal Survival: A Systematic Review and Meta-Analysis 1. 5. 2 1 1 1 1 Yu-Hao Zhou , Li-Gong Tang , Shi-Lei Guo , Zhi-Chao Jin , Mei-Jing Wu , Jia-Jie Zang , Jin-Fang Xu , 1 1 3 1 6 4 1 Chun-Fang Wu , Ying-Yi Qin , Qing Cai , Qing-Bin Gao , Shan-Shan Zhang , Dand-Hui Yu , Jia He * 1 Department of Health Statistics, Second Military Medical University, Shanghai, China, 2 Department of Anatomy, Second Military University, Shanghai, China, 3 Department of Rheumatology and Immunology, Changhai Hospital, Second Military Medical University, Shanghai, China, 4 Academic Journal of Second Military Medical University, Shanghai, China, 5 Department of Urology, Wuhan General Hospital, Guangzhou Command PLA, Wuhan, China, 6 Tumor Immunology and Gene Therapy Center, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China Abstract Background: Studies have shown that steroids can improve kidney survival and decrease the risk of proteinuria in patients with Immunoglobulin A nephropathy, but the overall benefit of steroids in the treatment of Immunoglobulin A nephropathy remains controversial. The aim of this study was to evaluate the benefits and risks of steroids for renal survival in adults with Immunoglobulin A nephropathy. Methodology and Principal Findings: We searched the Cochrane Renal Group Specialized Register, Cochrane Controlled Trial Registry, MEDLINE and EMBASE databases. All eligible studies were measuring at least one of the followi