association between leukocyte and metabolic syndrome in urban han chinese a longitudinal cohort study白细胞与代谢综合征之间的关系在城市汉族纵向队列研究.pdf

Association between Leukocyte and Metabolic Syndrome in Urban Han Chinese: A Longitudinal Cohort Study 1. 2. 1 3 3 3 Wenjia Meng , Chengqi Zhang , Qian Zhang , Xinhong Song , Haiyan Lin , Dongzhi Zhang , 1 1 1 1 2 4 1 Yongyuan Zhang , Zhenxin Zhu , Shuo Wu , Yanxun Liu , Fang Tang , Xiaowei Yang , Fuzhong Xue * 1 Department of Epidemiology and Health Statistics, School of Public Health, Shandong University, Jinan, China, 2 Health Management Center, Shandong Provincial QianFoShan Hospital, Jinan, China, 3 Center for Health Management, Provincial Hospital Affiliated to Shandong University, Jinan, China, 4 Department of Public Health Sciences, School of Medicine, University of California Davis, Davis, California, United States of America Abstract Background: Although cross-sectional studies have shown that leukocyte is linked with metabolic syndrome (MetS), few longitudinal or cohort studies have been used to confirm this relationship. We therefore conducted a large-scale health check-up longitudinal cohort in urban Chinese population from middle to upper socioeconomic strata to investigate and prove the association between the total leukocyte/its subtypes and MetS/its components (obesity, hyperglycemia, dyslipidemia, and hypertension). Methods: A longitudinal cohort study was established in 2005 on individuals who were middle-to-upper class urban Chinese. Data used in this investigation was based on 6,513 participants who had at least three routine health check-ups over a period of six-year follow-up. Data analysis was conducted thro