burden of disease caused by otitis media systematic review and global estimates疾病负担中耳炎引起的系统回顾和全球估计.pdf

Burden of Disease Caused by Otitis Media: Systematic Review and Global Estimates 1 1 2 1 3 Lorenzo Monasta *, Luca Ronfani , Federico Marchetti , Marcella Montico , Liza Vecchi Brumatti , 4 5 1 3 Alessandro Bavcar , Domenico Grasso , Chiara Barbiero , Giorgio Tamburlini 1 Epidemiology and Biostatistics Unit, Institute for Maternal and Child Health - IRCCS ‘‘Burlo Garofolo’’, Trieste, Italy, 2 Department of Paediatrics, Institute for Maternal and Child Health - IRCCS ‘‘Burlo Garofolo’’, Trieste, Italy, 3 Research Direction, Institute for Maternal and Child Health - IRCCS ‘‘Burlo Garofolo’’, Trieste, Italy, 4 Unit for Health Services Research and International Health, Institute for Maternal and Child Health - IRCCS ‘‘Burlo Garofolo’’, Trieste, Italy, 5 Ear, Nose and Throat Unit, Department of Paediatric Surgery, Institute for Maternal and Child Health - IRCCS ‘‘Burlo Garofolo’’, Trieste, Italy Abstract Background: Otitis media (OM) is a leading cause of health care visits and drugs prescription. Its complications and sequelae are important causes of preventable hearing loss, particularly in developing countries. Within the Global Burden of Diseases, Injuries, and Risk Factors Study, for the year 2005 we estimated the incidence of acute OM, chronic suppurative OM, and related hearing loss and mortality for all ages and the 21 WHO regional areas. Methods: We identified risk factors, complications and sequelae of OM. We carried out an extensive literature review (Medline, Embase, Lilacs and Wholis) which lead to the selection of 114 papers comprising relevant data. Data were available from 15 of the 21 WHO regions.