the genome of the obligate intracellular parasite trachipleistophora hominis new insights into microsporidian genome dynamics and reductive evolution专性细胞内寄生虫的基因组trachipleistophora hominis洞察microsporidian基因组进化动力学和还原.pdf

The Genome of the Obligate Intracellular Parasite Trachipleistophora hominis : New Insights into Microsporidian Genome Dynamics and Reductive Evolution 1 1 1 ¨ 1 1 1 Eva Heinz , Tom A. Williams , Sirintra Nakjang , Christophe J. Noel , Daniel C. Swan , Alina V. Goldberg , 1 2 3 ¨ 4 ¨ 4 5 Simon R. Harris , Thomas Weinmaier , Stephanie Markert , Dorte Becher , Jorg Bernhardt , Tal Dagan , 6 6 3 2 7 1 Christian Hacker , John M. Lucocq , Thomas Schweder , Thomas Rattei , Neil Hall , Robert P. Hirt *, T. Martin Embley1* 1 Institute for Cell and Molecular Biosciences, The Medical School, Newcastle University, Newcastle upon Tyne, United Kingdom, 2 Department of Computational Systems Biology, University of Vienna, Vienna, Austria, 3 Institute of Pharmacy, Ernst-Moritz-Arndt-University Greifswald, Greifswald, Germany, 4 Institute of Microbiology, Ernst- ¨ ¨ Moritz-Arndt-University Greifswald, Greifswald, Germany, 5 Institute for Molecular Evolution, Heinrich Heine University Dusseldorf, Dusseldorf, Germany, 6 School of Medicine, University of St Andrews, St Andrews, Scotland, 7 Department of Functional and Comparative Genomics, School of Biological Sciences, University of Liverpool, Liverpool, United Kingdom Abstract The dynamics of reductive genome evolution for eukaryotes living inside other eukaryotic cells are poorl