the genetic structure of leishmania infantum populations in brazil and its possible association with the transmission cycle of visceral leishmaniasis婴儿利什曼虫种群的遗传结构在巴西和它可能与内脏利什曼病的传播循环.pdf

The Genetic Structure of Leishmania infantum Populations in Brazil and Its Possible Association with the Transmission Cycle of Visceral Leishmaniasis 1,2 1 3 Gabriel Eduardo Melim Ferreira *, Barbara Neves dos Santos , Maria Elizabeth Cavalheiros Dorval , 4 1 2 1 Tereza Pompilio Bastos Ramos , Renato Porrozzi , Alexandre Afranio Peixoto , Elisa Cupolillo ´ ˜ ´ 1 Laboratorio de Pesquisa em Leishmaniose, Instituto Oswaldo Cruz – Fundac¸ao Oswaldo Cruz, Rio de Janeiro, Brasil, 2 Laboratorio de Biologia Molecular de Insetos, ˜ ˆ ´ ´ Instituto Oswaldo Cruz – Fundac¸ao Oswaldo Cruz, Rio de Janeiro, Brasil, 3 Centro de Ciencias Biologicas e da Saude, Universidade Federal do Mato Grosso do Sul – Mato ´ ˆ ˆ ´ ˆ ´ Grosso do Sul, Brasil, 4 Secretaria de Estado de Saude do Mato Grosso, Superintendencia de Vigilancia em Saude, Coordenadoria de Vigilancia em Saude Ambiental, Mato Grosso, Brasil Abstract Leishmania infantum is the etiologic agent of visceral leishmaniasis (VL) in the Americas, Mediterranean basin and West and Central Asia. Although the geographic structure of L. infantum populations from the Old World have been described, few studies have addressed the populatio