各期糖尿病视网膜病变患者房水中PEDF与OPs相关性分析.pdf

Hans Journal of Ophthalmology 眼科学, 2016, 5(1), 22-28 Published Online March 2016 in Hans. /journal/hjo /10.12677/hjo.2016.51005 Aqueous Humor Levels of Pigment Epithelium-Derived Factor and Oscillatory Potentials in Diabetic Retinopathy Patients 1* 2 1 1 1 Jing Zang , Guoqi Guan , Wenjuan Wang , Jionglin Bao , Lilun Chen 1 Department of Ophthalmology, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou Guangdong 2 Jinan University, Guangzhou Guangdong nd th th Received: Mar. 2 2016; accepted: Mar. 25 , 2016; published: Mar. 29 , 2016 Copyright © 2016 by authors and Hans Publishers Inc. This work is licensed under the Creative Commons Attribution International License (CC BY). /licenses/by/4.0/ Abstract Objective: To investigate the relationship between pigment epithelium derived factor (PEDF) and oscillatory potentials (OPs) in various diabetic retinopathy and to provide an objective basis for the early diagnosis of diabetic retinopathy (diabetic retinopathy, DR) and the prediction of the progression of the disease. Methods: Aqueous humor samples were collected from 40 eyes of 40 type 2 diabetes patients, including 19 eyes without diabetic retinopathy and 21 eyes with diabetic (11 eyes with NPDR and 10 eyes with PDR), twenty aqueous samples from 20 cataract patients without other ocular or systemic diseases served as controls. The PEDF levels in aqueous humor were measured by enzyme-linked immunosorbent assay (ELISA). The total amplitude of OPs in the whole retina was detected by the Roland visual el