王延君慢性乙型肝炎患者血脂相关指标检测和临床意义.doc

慢性乙型肝炎患者检测临床意义 李群 杨敏 （潍坊医学院 山东 潍坊 2610） 【摘要】 目的 通过慢性乙型肝炎(CHB)患者来其。方法 结果结论【关键词】Detection of serum lipids of patients with chronic hepatitis B and its clinical significance Wang Yan jun，LI Qun，（Department of Infectious Disease Weifang Medical College,Weifang　261053）BSTRACT】 Objective Through detecting the blood lipid related indexes of chronic hepatitis B (CHB) pations to study the judgment of which on the degree of liver injury. Methods randomly selecting 40 patients with pure CHB, 30 patients with liver cirrhosis after hepatitis B, and 40 cases of healthy controls (HC) as the object of study. Than detecting blood lipid indexes related to detection: triglyceride (TG), total cholesterol (CHO), high density lipoprotein (HDL-C), apolipoprotein A1 (APoA1), apolipoprotein B100 (APoB100), relevant indicators of liver function: alanine aminotransferase (ALT), total bilirubin (TBiL). According to the detecting results, a retrospective analysis of the correlation between blood lipid indexes and glutamic pyruvic transaminase, total bilirubin, blood lipid index to reflect the degree of liver injury.Results The blood lipid levels of both pure chronic hepatitis B and cirrhosis of hepatitis B patients made significantly difficulty, they are higher than the blood lipid levels of the healthy control group (P 0.05). Then to analyze the relevance between serum CHO, TG, HDL-C, APoA1, APoB100 and serum ALT, TBiL of pations infected HBV,finding a significant negative correlation between them(P0.05).Conclusions Blood lipid related indexes of chronic hepatitis B patients was significantly lower than the healthy people and can reflect the damage degree of liver, it’s necessary to detecting and follow-up the blood lipid related indexes of CH B patients, including TG, CHO. 【KEY WORDS】CB，CHO， TG，Apolipoprotein， ALT，TBil 肝脏参与合成脂蛋白并参与合成脂蛋白代谢的酶，又是各种脂蛋白降解的重要部位，在脂类代谢中有着举足轻重的地位。慢性乙型肝炎资料与方法 1一般资料 选择潍坊医学院附属医院感染科住院确诊的CHB患者例作为CHB组，例，所有CHB病例诊断均符合201年中华医学会肝病学分会、感染病学分会修订的《慢性乙型肝炎防治指南》［］的命名和诊断标准。所