assessment of prenatal exposure to arsenic in tenerife island评估产前暴露于砷在特内里费岛.pdf

Assessment of Prenatal Exposure to Arsenic in Tenerife Island 1,2,3,4 ´ 5 1,2,3,4 1,2 6 Oriol Vall , Mario Gomez-Culebras , Oscar Garcia-Algar *, Xavier Joya , Dinoraz Velez , ´ 5, Carme Puig 1,2 Eva Rodrıguez-Carrasco ` ` 1 Unitat de Recerca Infancia i Entorn (URIE), Institut Hospital del Mar d’Investigacions Mediques (IMIM), Barcelona, Spain, 2 Red Samid, Retic, Instituto de Salud Carlos III, ` ´ ´ Madrid, Spain, 3 Servei de Pediatria, Hospital del Mar, Barcelona, Spain, 4 Universitat Autonoma de Barcelona, Barcelona, Spain, 5 Departamento de Cirugıa Pediatrica, ´ ´ ´ Universidad de Tenerife, Tenerife, Spain, 6 Instituto de Agroquımica y Tecnologıa de Alimentos, Consejo Superior de Investigaciones Cientıficas (IATA-CSIC), Valencia, Spain Abstract Introduction: Increasing awareness of the potential chronic health effects of arsenic (As) at low exposure levels has motivated efforts to better understand impaired child development during pregnancy by biomarkers of exposure. The aims of this study were to evaluate the prenatal exposure to As by analysis of an alternative matrix (meconium), to examine its effects on neonatal outcomes and investigate the association with maternal l