《结肠癌肝转移》ppt课件.ppt

结直肠癌肝转移;结直肠癌肝转移分类;肝转移灶手术的适应证;肝转移灶手术的禁忌症;结直肠癌肝转移可切除的定义;同时性切除;分阶段切除;手术方式;推荐;推荐;liver metastases;新辅助化疗优势;Adjuvant, neoadjuvant, conversion therapy for CRC liver metastases;EORTC phase III study 40983研究设计;EORTC Study 40983;乐沙定，伊立替康和持续滴注5-FULV(FOLFOXIRI)两周方案和Folfiri相比一线治疗转移性结直肠癌： III期临床结果（GONO）;;A. Falcone, ASCO GI 2006, #227;Rescue Surgery for Unresectable Colorectal Liver Metastases Downstaged by ChemotherapyA Model to Predict Long-term Survival;Resection of liver metastases: non-selected patients treated with targeted/cytotoxic agents;Liver-limited disease PFS and RR in KRAS wild-type;Randomized multicenter study of cetuximab plus FOLFOX or cetuximab plus FOLFIRI in neoadjuvant treatment of non-resectable colorectal liver metastases (CELIM study) ;Efficacy: Confirmed Response;Resections;手术前化疗时限;;手术前化疗的关注问题;谢谢！