奥氮平联合舒必利治疗难治性精神分裂症临床效果探析.doc
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奥氮平联合舒必利治疗难治性精神分裂症临床效果探析 [摘要] 目的 分析并探?奥氮平联合舒必利治疗难治性精神分裂症的临床效果,从而为临床治疗方案选择提供依据。方法 随机选取2014年6月―2016年6月在医院接受治疗的难治性精神分裂症患者120例为研究对象,随机分为观察组与对照组,每组60例。观察组给予奥氮平联合舒必利治疗,对照组仅给予奥氮平治疗。结果 观察组治疗有效率为70.00%,对照组治疗有效率为51.67%。观察组治疗有效率明显高于对照组(P0.05)。 结论 奥氮平联合舒必利治疗难治性精神分裂症的临床效果显著,症状改善明显,值得临床推广
[关键词] 奥氮平;舒必利;精神分裂症;临床效果
[中图分类号] R749 [文献标识码] A [文章编号] 1674-0742(2017)01(c)-0122-04
Analysis of Clinical Effect of Olanzapinerexa Combined with Sulpiride in Treatment of Treatment-resistant Schizophrenia
LIANG Jin-hai
Department of Psychiatry, Nanan Rehabilitation Hospital, Nanan, Fujian Province, 362360 China
[Abstract] Objective To analyze the clinical effect of olanzapinerexa combined with sulpiride in treatment of treatment-resistant schizophrenia thus providing basis for the choice of the clinical treatment plan. Methods 120 cases of patients with treatment-resistant schizophrenia treated in our hospital from June 2014 to June 2016 were random selected as the research objects and randomly divided into two groups with 60 cases in each, the observation group were treated with olanzapinerexa combined with sulpiride, while the control group were treated with simple olanzapinerexa. Results The treatment effective rate in the observation group was obviously higher than that in the control group(70.00% vs 51.67%),(P0.05). Conclusion The clinical effect of olanzapinerexa combined with sulpiride in treatment of treatment-resistant schizophrenia is obvious, and the improvement of symptoms is obvious, which is worth clinical promotion.
[Key words] Olanzapinerexa; Sulpiride; Schizophrenia; Clinical effect 精神分裂症是一种慢性精神疾病,阴性症状及认知功能障碍均造成其无法独立自主生活,身心健康受损[1]。而难治性精神分裂症,大约占精神分裂症人数的30%,大多数划分方式主要根据既往应用治疗药物无效的数量来划分,但目前尚无明确定义[2]。难治性精神分裂症因治疗难度大、患者复发次数多,加重患者及其家属的精神、心理、经济等方面痛苦,如何选择治疗方式已经成为精神科一大难题[3]。该次研究随机选取2014年6月―2016年6月在医院接受治疗的难治性精神分裂症患者120例为研究对象,分析并探讨奥氮平联合舒必利治疗难治性精神分裂症的临床效果,从而为临床治疗方案选择提供依据,现报道如下
1 资料与方法
1.1 一般资料
随机选取在医院接受治疗的难治性精神分裂症患者120例为研究对象。男67例,女53例,年18~58岁,平均(36.23±3.16)岁,平
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