survey of recent situation of chromosome pathology in different breeds of german cattle近况的调查不同品种的染色体病理学的德国牛.pdf

Survey of recent situation of chromosome pathology in different breeds of cattle(1) german A. HERZOG, Henni HÖHN G. W. RIECK Institut für Zuchthygiene und Vetevinavmedizinische Genetik der Justus-Liebig-Univevsitat Giessen, Holmannstasseyoz D-6oo3Giessen p(Bundesre.Deutschland) Summary i. With the aim to elucidate the etiological role of chromosome anomalies in pathology of domestic animals karyotype analyses had been performed routinically in 478newborn calves with congenital malformations, furthermore in adult cattle with hereditary diseases, andin individuals with malformations of genital organs. The investigations have been realized during the past 10 years within the three large breeds of the cattle population of Hessen. Chromosome ano- malies of different types have been found in 141 probands. 2. Considering the impossibility in karyotyping all calves with congenital anomalies exten- sively, most of them being stillborn, and in regard of the impractibility of a cytogenetic explo- ration of whole the population, it seems to be impossible to derive more than rough estimations of the real frequencies of chromosome anomalies within the observed population. 3. The first rank of different types of chromosome anomalies is occupied by the z /29 trans- location, followed by the trisomy 8.1 (In this connection the XX /XY chimerism in freemartins is not taken in consideration because its frequency is depending exclusively from the frequencies of heterozygous twins within the different breeds). Considering their real frequencies both types of chromosome anomalies dont possess a noteworthy economical importance within the observed population in the present situatio