基因组信息学10.pdf

Methylation-seq Epigenome DNA Methylation The mystery of DNA demethylation Next-generation Application Outline Homework • 回顾课堂介绍的新一代测序应用，选择其 中一种，设计解决某一个生物学问题或现 象（如疾病机理等），写出研究方案，包 括：所用实验方法、数据、分析流程、拟 得到的结果。 • 姓名_学号_题目.doc/docx • 9月30号前发到邮箱： zhihui013201@ • 邮件主题：姓名_学号_作业 第七节第三代测序技术 • Third generation technologies aim to increase throughput and decrease the time to result and cost by eliminating the need for excessive reagents and harnessing the processivity of DNA polymerase Technology • Ion semiconductor sequencing • 离子半导体测序 • DNA nanoball sequencing • DNA 纳米球测序 • Helioscope single molecule sequencing • Single molecule SMRT(TM) sequencing • Single molecule real time (RNAP) sequencing • Nanopore DNA sequencing • Video SMRT • Video 小结