the antimicrobial properties of cedar leaf (thuja plicata) oil; a safe and efficient decontamination agent for buildings雪松叶的抗菌性(金钟柏plicata)油;.pdf

Int. J. Environ. Res. Public Health 2011, 8, 4477-4487; doi:10.3390/ijerph8124477 OPEN ACCESS International Journal of Environmental Research and Public Health ISSN 1660-4601 /journal/ijerph Article The Antimicrobial Properties of Cedar Leaf (Thuja plicata) Oil; A Safe and Efficient Decontamination Agent for Buildings James Hudson *, Michael Kuo and Selvarani Vimalanathan Department of Pathology Laboratory Medicine, University of British Columbia, 2733 Heather Street, Vancouver, BC V5Z 3J5, Canada; E-Mails: mkuo1@sfu.ca (M.K.); vnathanm@ (S.V.) * Author to whom correspondence should be addressed; E-Mail: jbhudson@interchange.ubc.ca ; Tel.: +1-604-875-4351; Fax: +1-604-875-4351. Received: 18 October 2011; in revised form: 25 November 2011 / Accepted: 28 November 2011 / Published: 30 November 2011 Abstract: Cedar leaf oil (CLO), derived from the Western red cedar, Thuja plicata, was evaluated as a safe and acceptable broad spectrum antimicrobial agent, with a view to its potential applications in buildings, including the alleviation of sick building syndrome. Various Gram-positive and Gram-negative human bacteria, and two fungal organisms, all known to be common environmental sources of potential infection, were selected and tested quantitatively, and all of them were found to be susceptible