simple mild and efficient method for the preparation of一种简单高效方法.pdf

Tetrahedron70(2014)9814e9818

ContentslistsavailableatScienceDirect

Tetrahedron

journalhomepage:

Asimple,mild,andefficientmethodforthepreparationofa,a-

dichloroketoneswithDCDMHcatalyzedbyammoniumchloride

ZubiaoZheng*,BingbingHan,PengCheng,JiangxiuNiu,AidongWang

DepartmentofChemistry,HuangshanUniversity,AnHui245041,

articleinfo

Articlehistory:Newprocessthatcanselectivelypreparea,a-dichloroketonesfromvariousketoneswith1,3-dichloro-

Received25August20145,5-dimethylhydantoin(DCDMH)usingammoniumchlorideasacatalystisreported.Theeffectsof

Receivedinrevisedform21October2014ammoniumsalts,solvents,DCDMH,andreactiontemperaturewereinvestigated.Undertheoptimal

Accepted3November2014

condition,mostofa,a-dichlorinatedproductswereselectivelyobtainedin86e98%yield.

Availableonline13November2014

2014ElsevierLtd.

Keywords:

Ketones

Dichlorination

1,3-Dichloro-5,5-dimethylhydantoin

a,a-Dichloroketone

Ammoniumchloride

1.Introduction1,3-Dichloro-5,5-dimethylhydantoin(DCDMH)isdisinfecting

agentandbleachingagentthathasbeenextensivelyemployedin

Chlorinatedorganiccompoundsarehighlyversatilestartingindustrialanddomesticwater