decrypting the mitochondrial gene pool of modern panamanians现代巴拿马的解密线粒体基因池.pdf

Decrypting the Mitochondrial Gene Pool of Modern Panamanians 1. 2. 3. 1,4 1 Ugo A. Perego , Hovirag Lancioni , Maribel Tribaldos , Norman Angerhofer , Jayne E. Ekins , 5 1,4 3 6 3 Anna Olivieri , Scott R. Woodward , Juan Miguel Pascale , Richard Cooke , Jorge Motta , Alessandro Achilli2* ` 1 Sorenson Molecular Genealogy Foundation, Salt Lake City, Utah, United States of America, 2 Dipartimento di Biologia Cellulare e Ambientale, Universita di Perugia, Perugia, Italy, 3 Instituto Conmemorativo Gorgas de Estudios de la Salud, Panama City, Panama, 4 Ancestry, Provo, Utah, United States of America, 5 Dipartimento di ` ´ Biologia e Biotecnologie, Universita di Pavia, Pavia, Italy, 6 Smithsonian Tropical Research Institute, Apdo, Ancon, Panama Abstract The Isthmus of Panama–the narrow neck of land connecting the northern and southern American landmasses–was an obligatory corridor for the Paleo-Indians as they moved into South America. Archaeological evidence suggests an unbroken link between modern natives and their Paleo-Indian ancestors in some areas of Panama, even if the surviving indigenous groups account for only 12.3% of the total population. To evaluate