第十二章 细胞分化与基因表达调控（Chapter 12 regulation of cell differentiation and gene expression）.doc

第十二章 细胞分化与基因表达调控（Chapter 12 regulation of cell differentiation and gene expression） Chapter 12 regulation of cell differentiation and gene expression 1. Understand the concept and control mechanism of cell differentiation, and master basic concepts such as housekeeping gene, luxury gene, cell totipotency and stem cells. 2. Understand the molecular mechanism of cell carcinogenesis and the basic characteristics of cancer cells. Understand the regulatory mechanism of eukaryotic gene expression in transcription level, post-transcriptional level and translation level. Ii. Teaching focus: 1. The nature of cell differentiation and its influencing factors; The molecular mechanism of cell carcinogenesis and the basic characteristics of cancer cells. 3. Teaching difficulties: gene regulation of transcription level. Iv. Teaching methods and teaching methods: teaching, discussion and multimedia assisted instruction. Iv. Teaching contents: In the process of the normal development of the individual, through increase the control of cell division and cell number, through the orderly cell differentiation and increase the cell type, and then by the different types of tissue and organ cells of living organisms, perform different functions. It is clear that cell differentiation is a kind of cell group that performs various complex and special biological functions through mutual synergism, which lays the foundation for the development and evolution of life at a higher level. Cell differentiation, cell differentiation) : in ontogenesis, by a kind of the same cell type after cell division gradually forming stability differences in morphology, structure and function, the produce process of different groups of cells. Its essence lies in the difference expression of tissue specific genes in time and space Cell differentiation is the foundation and core of multicellular organism development. The key to cell differentiation is the synthesis of specific proteins. The synthesis of specific prote