抗生素应用（Antibiotic application）.doc

抗生素应用（Antibiotic application） The rational application of antibiotics 2011-06-03 20:02 [I want to correct the error] 1. Reasonable application of the concept of antibiotics The clinical pharmacological concept of rational use of antibiotics is a safe and effective use of antibiotics, which is to ensure that they are effective under the precondition of safety, which is the basic principle of rational use of antibiotics. Under normal circumstances, most of the new antibiotics in several years will lose its effectiveness by bacteria resistant, incorrect use, however, is adding to the drug-resistant bacteria growing rapidly. Due to the complexity of the application of antibiotics in the clinical application, the variety of varieties, the rapid updating and the various kinds of drugs are complicated, the combination of drugs is increasing, and the prevention of drug use is becoming more and more widespread. Therefore, the incidence of adverse reactions and drug resistance of antibacterial drugs are still increasing year by year. Rational use of antibiotics should be analyzed by specific patients, and individualized treatments are developed. No fixed solution can be applied in different situations. The author thinks that rational choice and rational use are two crucial problems of rational use of antibiotics. 2. Clinical selection of antibiotics 2.1 must first master the antibiotics antibacterial spectrum characteristics of different types of antibiotics has different, so the antibacterial spectrum of the selected drug be sure to make it compatible with infection by microorganisms, otherwise, they dont have is a waste of money, and delay treatment. 2.2 choose antibiotics according to the sensitivity of the pathogenic bacteria such as from January 1, 1997 to March 31, 1997, the main pathogenic bacteria was isolated 1841 strains in clinical specimens, including 429 strains klebsiella pneumonia, nitrate negative bacilli 307 strains of e. coli 306 strains, 284 strains staphyl