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Molecules 2011, 16, 9404-9420; doi:10.3390/molecule OPEN ACCESS molecules ISSN 1420-3049 /journal/molecules Article Succinobucol’s New Coat — Conjugation with Steroids to Alter Its Drug Effect and Bioavailability Ondřej Jurček 1,2,3,*, Satu Ikonen 1, Lucie Buřičová 2,3, Martina Wimmerová 2,3, Zdeněk Wimmer 2,3, Pavel Drašar 3, Jan Horníček 3,4, Adéla Galandáková 5, Jitka Ulrichová 5 and Erkki T. Kolehmainen 1 1 Department of Chemistry, FI-40014, University of Jyväskylä, P.O. Box 35, Finland; E-Mails: satu.m.ikonen@ (S.I.); erkki.t.kolehmainen@jyu.fi (E.T.K.) 2 Isotope Laboratory, Institute of Experimental Botany, Academy of Sciences of the Czech Republic, Vídeňská 1083, 14220, Prague 4, Czech Republic; E-Mails: lucie.buricova@ (L.B.); martina.wimmerova@vscht.cz (M.W.); wimmer@biomed.cas.cz (Z.W.) 3 Institute of Chemical Technology, Prague, Technická 5, 16628, Prague 6, Czech Republic; E-Mail: pavel.drasar@vscht.cz 4 Department of Spectroscopy and Physical Organic Chemistry, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 16610, Prague 6, Czech Republic; E-Mail: hornicek@uochb.cas.cz 5 Palacký University in Olomouc, Institute of Translational and Molecular Medicine, Hněvotínská 3, 77515, Olomouc, Czech Republic; E-Mails: Alfa.Baba@seznam.cz (A.G.); JitkaUlrichova@seznam.cz (J.U.) * Author to whom correspondence should be addressed; E-Mail: jurcekondrej@; Tel.: +358-458-857-363; Fax: +358-14-260-2501. Received: 29 September 2011; in revised form: 2 November 2011 / Accepted: 7 November 2011 / Published: 10 Novem