appropriate modeling of infectious diseases适当的传染病模型.pdf

Open access, freely available online Synopses of Research Articles Which Treatment for Postherpetic Neuralgia? DOI: 10.1371/journal.pmed.0020238 Postherpetic neuralgia (PHN) is a orally administered therapies, such as might be hazardous, and the authors and chronically painful condition that is a tricyclic antidepressants, some opioids, other researchers have concluded that complication of shingles (acute herpes gabapentin, tramadol, and pregabalin. further high-quality trials of this therapy zoster), a recurrence of the varicella- Some topically administered therapies, are needed. The authors found little zoster virus, which initially causes such as lidocaine and capsaicin, were evidence regarding possible synergistic chickenpox. Although shingles usually associated with analgesic effi cacy in effects of the various treatments to resolves within a month, some people selected patients. However, it appeared support or refute the concomitant use of continue to feel the pain of PHN long that therapies such as oral administration combinations of drugs. after the rash and blisters heal, because of of certain NMDA receptor antagonists, They stressed that any treatment nerve damage (neuropathic pain) caused codeine, ibuprofen, lorazepam, 5HT1 plan must recognise the importance of by the shingles. Not everyone who has receptor agonists, and acyclovir were not the biopsychosocial model of chronic had shingles develops PHN, although it effi cacious in PHN.