technology innovation for infectious diseases in the developing world技术创新为发展中国家传染病的问题.pdf

So and Ruiz-Esparza Infectious Diseases of poverty 2012, 1:2 /content/1/1/2 OPINION Open Access Technology innovation for infectious diseases in the developing world * Anthony D So and Quentin Ruiz-Esparza Abstract Enabling innovation and access to health technologies remains a key strategy in combating infectious diseases in low- and middle-income countries (LMICs). However, a gulf between paying markets and the endemicity of such diseases has contributed to the dearth of RD in meeting these public health needs. While the pharmaceutical industry views emerging economies as potential new markets, most of the world’s poorest bottom billion now reside in middle-income countries–a fact that has complicated tiered access arrangements. However, product development partnerships–particularly those involving academic institutions and small firms–find commercial opportunities in pursuing even neglected diseases; and a growing pharmaceutical sector in BRICS countries offers hope for an indigenous base of innovation. Such innovation will be shaped by 1) access to building blocks of knowledge; 2) strategic use of intellectual property and innovative financing to meet public health goals; 3) collaborative norms of open innovation; and 4) alternative business models, some with a double bottom line. Facing such resource constraints, LMICs are poised to develop a new, more resource-effective model of innovation that holds exciting promise in meeting the needs of global health. Keywords: Innovation, Technology, Access, Policy, Public health, RD collaboration, RD, Business model, Open source, Open innovation Multilingual abstracts like schistosomiasis, hookworm and malaria contribute to Please see Additional file 1 for translations of the abst