PAMAM改性BPPO中空纤维膜的合成表征及应用的中期报告.docx

PAMAM改性BPPO中空纤维膜的合成表征及应用的中期报告 摘要： 中空纤维膜（HFM）因其大孔径和高通量而成为膜分离技术中的关键材料。然而，HFM 常常受到蛋白质吸附和污染的影响，降低了其分离效率和稳定性。因此，本研究旨在通过 PAMAM 改性，改善 HFM 的抗蛋白质吸附性能，从而提高其分离效率和稳定性。在实验中，我们首先利用相分离法制备了含有不同浓度的 PAMAM 溶液，并将其用于改性 BPPO HFM 的制备。然后，利用 FT-IR、SEM、XPS 等技术对 PAMAM 改性后的 HFM 进行表征，并评估其抗蛋白质吸附性能。初步结果显示，PAMAM 改性后的 HFM 具有较高的抗蛋白质吸附能力，其分离效率和稳定性也有所提高。未来研究将进一步探究 PAMAM 改性对 HFM 的生物相容性和可持续性的影响。 Abstract： Hollow fiber membranes (HFMs) have become critical materials in membrane separation technologies due to their large pore size and high flux. However, HFMs are often susceptible to protein adsorption and contamination, reducing their separation efficiency and stability. Therefore, the aim of this study is to improve the anti-protein adhesion properties of HFMs by PAMAM modification, thereby enhancing their separation efficiency and stability. In this experiment, we first prepared PAMAM solutions with different concentrations using phase separation method and used them to prepare modified BPPO HFMs. Then, we characterized the PAMAM-modified HFMs using FT-IR, SEM, XPS, and evaluated their anti-protein adhesion properties. Preliminary results showed that PAMAM-modified HFMs had high anti-protein adhesion ability, and their separation efficiency and stability were also improved. Future studies will further explore the impact of PAMAM modification on the biocompatibility and sustainability of HFMs.