磁共振弥散张量成像观察创伤性胼胝体损伤.pdf

DOI :10.13929/j.1003 -3289.2008.11.01 中国医学影像技术2008 年第24 卷第 11期　Chin J M ed Imaging T echnol, 2008, Vol 24, No 11 ·1715 · 　中枢神经影像学 Magnetic resonance diffusion tensor imaging in traumatic corpus callosum injury 1 ＊ 2 3 4 4 WANGShuang-kun , LIUBai-yun , CHENGHua , AI Lin , DAI Jian-p ing , 4 4 4 GAOPei-yi , MAJun , LI Shao-wu (1.Depart ent of Radiology, theBeij ing Chaoyang Hospital Af f iliated to Capital University of Medical Science, Beij ing 100020, China;2.Depart ent of Neurosurgery , 4.Neuroi aging Center, Beij ing Tiantan Hosp ital, B eij ing 100050, China;3.Depart ent of Radiology , Beij ing Childrens Hospital Af f iliated to Capital University of Medical Science, Beij ing 100045, China) [Abstract]　Objective　To evaluate the potential clinical role for diffusion tensor imaging (DTI)in patients w ith traumatic corpus callosum injury.Methods　Tw enty-five closed traumatic brain injury patients (1 male, 9 female;age 20- 0, mean age 37)were evaluated by DTI with MR system.Quantitive analysis was performed using measurements of f ractional anisot- ropy (FA )and apparent diffusion coefficient (ADC)in the genu and splenium of corpus callosum.The measurements were correlated with the clinical Glasgow Coma Scale (GCS), and the outcomes were compared w ith those of 20 healthy subjects (12 male, 8 female;age 21- 0, mean age 3 ).Results　 FA values of patient group significantly reduced w ithin the genu and splenium of corpus callosum (P0.05), compared w ith the control group.There was no sig