socio-economic position and type 2 diabetes risk factors patterns in uk children of south asian, black african-caribbean and white european origin社会经济地位和2型糖尿病的风险因素模式在英国南亚的孩子,黑-加勒比和白色的欧洲血统.pdf
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Socio-Economic Position and Type 2 Diabetes Risk
Factors: Patterns in UK Children of South Asian, Black
African-Caribbean and White European Origin
1 1 1 1 1
Claudia Thomas *, Claire M. Nightingale , Angela S. Donin , Alicja R. Rudnicka , Christopher G. Owen ,
2 1 1
Naveed Sattar , Derek G. Cook , Peter H. Whincup
1 Population Health Research Centre, Division of Population Health Sciences and Education, St Georges, University of London, London, United Kingdom, 2 BHF Glasgow
Cardiovascular Research Centre, University of Glasgow, Glasgow, United Kingdom
Abstract
Background: Socio-economic position (SEP) and ethnicity influence type 2 diabetes mellitus (T2DM) risk in adults. However,
the influence of SEP on emerging T2DM risks in different ethnic groups and the contribution of SEP to ethnic differences in
T2DM risk in young people have been little studied. We examined the relationships between SEP and T2DM risk factors in
UK children of South Asian, black African-Caribbean and white European origin, using the official UK National Statistics
Socio-economic Classification (NS-SEC) and assessed the extent to which NS-SEC explained ethnic differences in T2DM risk
factors.
Methods and Findings: Cross-sectional school-based study of 4,804 UK children aged 9–10 years, including anthropometry
and fasting blood analytes (response rates 70%, 68% and 58% for schools, individuals and blood measurements).
Assessment of SEP was based on parental occupation defined using NS-SEC and ethnicity on parental self-report.
Associations between NS-SEC and adiposity, insulin resistance (IR) and triglyc
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