Diagnosis and Treatment of Mood Disorders That Co-occur With 发生与心境障碍的诊断和治疗.pdf

Diagnosis and Treatment of Mood Disorders That Co-occur With Schizophrenia MMiicchhaaeell AA.. EEssccaammiillllaa,, MM..DD.. Affective syndromes, particularly mania and depression, often occur noses on the basis of DSM-IV criteria during the course of illness in patients who have a diagnosis of schizo- without overlooking the syndromes phrenia. Our current diagnostic system allows clear classification of the that are present among patients who overlap of affective symptoms and psychotic symptoms. However, this have both a mood disorder and a diagnostic system will eventually require major revisions so that it will thought disorder. Finally, I review more accurately reflect the biologic mechanisms that underlie different current studies and issues in the symptoms. This article reviews the historical unerpinnings of the diag- treatment of mood syndromes that nostic classification of affective and psychotic symptoms, including a co-occur with schizophrenia. discussion of current diagnostic practices and a review of the few stud- ies on treatment of affective symptoms and syndromes in patients with Historical development of a schizophrenia. There is a great need for additional research on treat- psychopathologic terminology ment of mood disorders that arise during the course of schizophrenia, Although descriptions of mental ill- especially with regard to newer mood stabilizers and antidepressants. ness have been made throughout (Psychiatric Services 52:911–919, 2001) recorded history, rigor